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CyberKnife: Clinical information

How it works | What to expect | Information for physicians | Our team

Information for physicians

CyberKnife system features

The CyberKnife is the world's first and only full-body radiosurgery system. It combines real-time image guidance throughout treatment, unique Dynamic Motion Tracking™ and full-time robotics technology to treat tumors and lesions that were formerly inoperable. CyberKnife system features include:

Compact linear accelerator with express™
The compact X-band linear accelerator emits circular beams with secondary collimation ranging from 5mm to 60mm. This compact, lightweight system produces pencil-shaped beams of radiation that can be precisely delivered in almost any direction. This allows for superior conformality when treating patients.

Robotic manipulator
The CybeKnife's high-precision robotic manipulator is made by Kuka®, one of the world's leading manufacturers of robots. The robot is capable of delivering a repeatability accuracy of less than 0.2mm.

X-Ray sources
Low-energy x-ray sources generate two perpendicular, oblique, diagnostic x-rays that locate bony landmarks or implanted radiopaque markers throughout the treatment process.

Image detectors
High-resolution image detectors capture x-ray images and generate digital images of the patient's anatomy. New images are captured throughout treatment and are compared to the digitally reconstructed radiographs (DRRs) generated from the CT scans used in treatment planning. The imaging system then corrects for changes in the patient's position by sending a command to the robotic manipulator.

AXUM™ treatment couch
The AXUM Automatic Patient Positioning System automatically and accurately aligns patients in one simple step, significantly reducing patient set-up times and increasing patient throughput.

Synchrony™ respiratory tracking system
The Synchrony Respiratory Tracking System is the first technology in the world capable of delivering dynamic radiosurgery to targets that move with respiration. The CyberKnife system synchronizes the Robotic Delivery System with motion of the tumor, so margins of less than one millimeter are needed to compensate for respiration.

CyberKnife treatment planning system
The CyberKnife Treatment Planning System uses inverse and conformal planning techniques, which capitalize on the strengths of the system's unique delivery model.

Treatment planning

The CyberKnife's unique maneuverability offers the clinician a wider range of treatment options than conventional stereotactic radiosurgery devices. The treatment planning system is designed to support the clinician in determining the optimal treatment plan of individual patients, including beam weight, targeting positions, dose distributions and more.

Only the CyberKnife system offers all these planning and delivery options:

  • Inverse planning
  • Non-isocentric delivery
  • Hypofractionation

The system is based on CT scanning. MR images can be fused with the CT to provide optimal information on soft tissue as well as skeletal anatomy. CT angiography — injection of a contrast medium to demonstrate flow of fluid or blockage — is specifically useful in the treatment of arteriovenous malformations.

Patient immobilization

The CyberKnife system is the only stereotactic radiosurgery system that uses the body's skeletal structure as a reference frame. Depending on the area being treated by the CyberKnife system, the cranium or small implanted fiducials serve as the reference frame in current clinical applications.

With conventional stereotactic radiosurgery devices, the patient is fitted with a rigid, stereotactic frame prior to scanning. This instrument provides fiducial reference points for localization, as well as a means of immobilization during treatment. Immobilization is necessary to maintain a constant spatial relationship between the lesion and the radiation source to ensure accurate dose delivery. The patient wears the frame throughout the treatment process.

Elimination of the frame was a key factor in the development of the CyberKnife system. The use of a rigid stereotactic frame presents several drawbacks in treatment:

  • It can cause pain for the patient
  • It limits the use of fractionation
  • Fixation of the frame requires the use of some form of anesthesia and additional medical resources

To limit large movements, the patient may be fitted with a non-invasive flexible mesh mask. The CyberKnife system can also be adapted for use with a frame if the clinician prefers.

Localization

With the CyberKnife system, advanced image guidance technology tracks the target throughout treatment. The system repeatedly confirms target location in relationship to skeletal structure by processing radiographic images and correlating them to previously obtained CT scans. The imaging cameras detect any patient movement, and the CyberKnife system's linac is repositioned very accurately with respect to the target.

The CyberKnife system's use of stereotaxy for tumor localization differs from conventional stereotactic radiosurgery devices in several ways:

  • The CyberKnife uses true image guidance technology
  • The CyberKnife utilizes the skeletal structure of the body as its reference frame, eliminating the need for an invasive frame
  • The CyberKnife continually monitors and adjusts for patient movement during treatment

Treatment delivery

The CyberKnife system has several technological features that provide unmatched maneuverability in targeting tumors and lesions, including:

  • Compact 6-MV linear accelerator
  • Computer-controlled robotic arm with six degrees of freedom
  • Image guidance technology that eliminates the need for a rigid stereotactic frame and enables treatment of extra-cranial sites

When compared to conventional radiosurgery devices, the CyberKnife offers the advantage of:

  • Increased access to and coverage of target volume
  • Broader range of clinical applications, including:
      - Lesions in and around the cranium that are unreachable with other systems
      - Enhanced ability to avoid critical structures
      - Lesions in the neck and spine
      - Larger tumors
      - Otherwise inoperable tumors
      - Lesions throughout the body
      - Highly conformal dose distributions
  • Option of fractionated treatments
  • Option of targeting multiple tumors, in different locations, during a single treatment imaging and physician consultation are required to monitor your progress

CyberKnife treatment team at Aurora St. Luke's Medical Center is led by Kenneth Bastin, MD.

 

 



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