Xiaflex Injection

Dupuytren's Contracture Treatment

Philip Konkel, MD explains Xiaflex injections. View patients before and after treatment.
Warning: This video shows an actual surgical procedure and may not be suitable for all audiences.

Aurora Health Care surgeons are among the first to use a promising new therapy, Xiaflex® injection, to treat a condition called Dupuytren’s contracture.

Dupuytren’s contracture is an inherited condition that causes your fingers to curl toward your palm, and makes extending your fingers difficult or impossible. It's caused by the thickening and shortening of the fascia in the palm of your hand, a tissue that lies just below your skin. Some patients describe the feeling as "having a cord in my palm."

Until recently, surgery has been the only effective option for treating adults with Dupuytren’s contracture, which sometimes meant a long recovery and the need for physical therapy. The nonsurgical Xiaflex injection contains a mixture of proteins that are injected directly into your Dupuytren’s cord that helps break down collagen, one of the main cord components, to help straighten your finger. The FDA approved Xiaflex injections for use in early 2010.