Sheikh Khalifa bin Hamad Al Thani Center for Integrative Research on Cardiovascular Aging

Funding Support

Research on Cardiovascular AgingActive Support

Human Senescence and Cardioprotection
Principal Investigator: Arshad Jahangir, MD
National Heart, Lung and Blood Institute \ National Institutes of Health
7R01 HL089542-05                                       

The overall goal of this study is to identify aging-associated molecular defects that reduce tolerance of the human heart to injury and to identify therapeutic targets to prevent, slow or reverse changes that increase vulnerability of the aging atria to stress. 

Mitochondrial Dysfunction and Susceptibility to Atrial Fibrillation in the Elderly
Principal Investigator: Arshad Jahangir, MD
National Heart, Lung and Blood Institute \ National Institutes of Health
5R01 HL101240-04

The overall goal of this study is to gain insights into molecular mechanisms that promote changes in the aging human atria that increase risk for the development and progression of atrial fibrillation.

Completed Support 

Mitochondria and Cardioprotection in the Aging Human Heart
Principal Investigator: Arshad Jahangir, MD
Marriott Discovery Translational Mitochondrial Medicine Award 

CardioGerontology Research Laboratory, Mayo Clinic Arizona
Principal Investigator: Arshad Jahangir, MD
Angel and Paul Harvey Cardiovascular Research Endowment

Mitochondria and Surgical Myopreservation in the Elderly
Principal Investigator: Arshad Jahangir, MD
National Institute on Aging / National Institutes of Health
R01 AG 21201-03                                                                                                         

Changes in Gene Expression Underlying Increased Susceptibility of the Aging Heart to Injury
Principal Investigator: Arshad Jahangir, MD
Robert and Arlene Kogod Program on Aging Award

Myopreservation of the Senescent Heart
Principal Investigator: Arshad Jahangir, MD
National Scientist Development Grant / American Heart Association
AHA 02-30133N

Altered Energetics and Ca2+ Handling in Aging Human Atria Underlies Increased Susceptibility to AF Medicine Innovation Development and Advancement System, Mayo Clinic
Principal Investigator: Arshad Jahangir, MD
Award for Research in Cardiology. Department of Medicine, Mayo Clinic                      

Age-related Genomic and Proteomic Dynamics in Susceptibility of the Human Heart to Injury
Principal Investigator: Arshad Jahangir, MD
Medicine Innovation Development and Advancement System, Mayo Clinic

Aging and Mitochondria: Protective Role for a KATP Channel
Principal Investigator: Arshad Jahangir, MD
CR75 Research Award, Mayo Foundation for Education and Research

Aging and Mitochondrial Dysfunction
Principal Investigator: Arshad Jahangir, MD
Geriatric Cardiology Society Award in Basic Science

Electrical Activity in the Metabolically Compromised Heart
Principal Investigator: Arshad Jahangir, MD
Clinical Research (CR) Award Mayo Foundation

Developmental Changes in KATP Channel Expression and Regulation
Principal Investigator: Arshad Jahangir, MD
Clinical Research (CR20) Award Mayo Foundation