by Rick Alan
Rhabdomyolysis occurs when skeletal muscles are damaged and release myoglobin into the bloodstream. Myoglobin is an iron-containing pigment that can cause severe damage to the kidneys.
Rhabdomyolysis results from any condition that causes significant muscle damage. These include:
A risk factor is something that increases your chance of getting a disease or condition. Factors that may increase the risk of muscle damage include:
The most common symptoms include:
Other symptoms include:
In severe cases, rhabdomyolysis may result in:
The doctor will ask about your symptoms and medical history. A physical exam will be done. Tests may include:
Treatment may include:
Giving large amounts of fluid is the main treatment. Fluids are usually given by IV. Hydration helps to quickly flush myoglobin out of the kidneys to restore their function.
Medication may include:
Dialysis is a procedure that uses an artificial kidney machine to filter blood. The clean blood is then returned to your body.
Steps for prevention include:
National Institute of Health, US National Library of Medicine
National Kidney Foundation
The Kidney Foundation of Canada: British Columbia Branch
Criddle L. Rhabdomyolysis. Crit Care Nurse. 2003 Dec 23(6):14-30.
Rhabdomyolysis. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com. Updated January 26, 2011. Accessed October 17, 2012.
Sauret J, Marinides G. Rhabdomyolysis. Am Fam Physician. 2002 Mar 1:65(5):907-913.
Last reviewed October 2012 by Adrienne Carmack, MD