(te'' due gloo' tide)
WHY is this medicine prescribed?
Teduglutide injection is used to treat short bowel syndrome in people who need additional nutrition or fluids from intravenous (IV) therapy. Teduglutide injection is in a class of medications called glucagon-like peptide-2 (GLP-2) analogs. It works by improving the absorption of fluids and nutrients in the intestines.
HOW should this medicine be used?
Teduglutide comes as a powder to be mixed with liquid and injected subcutaneously (under the skin). It is usually injected once a day. Inject teduglutide at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Inject teduglutide exactly as directed. Do not inject more or less of it or inject it more often than prescribed by your doctor. If you inject more teduglutide than prescribed by your doctor, call your doctor right away.
Continue to use teduglutide even if you feel well. Do not stop using teduglutide without talking to your doctor.
You may inject teduglutide yourself or have a friend or relative give the injections. You and the person who will be injecting the medication should read the manufacturer's directions for mixing and injecting the medication before you use it for the first time at home. Ask your doctor to show you or the person who will be injecting teduglutide how to mix and inject it.
Teduglutide comes as a kit containing vials of teduglutide powder for injection, prefilled syringes containing diluent (liquid to be mixed with teduglutide powder), needles to attach to the diluent syringe, dosing syringes with needles attached, and alcohol swab pads. Throw away needles, syringes, and vials in a puncture-resistant container after you use them once. Ask your doctor or pharmacist how to dispose of the puncture-resistant container.
Always look at your teduglutide injection before you inject it. The solution should be clear and colorless or pale yellow, with no particles in it. Teduglutide must be used within 3 hours after mixing teduglutide powder with the diluent.
You can inject your teduglutide in your upper arm, thigh, or stomach. Never inject teduglutide into a vein or muscle. Use a different injection site each day. Do not inject teduglutide into any area that is tender, bruised, red, or hard.
Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with teduglutide injection and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( Web Site) to obtain the Medication Guide.
Are there OTHER USES for this medicine?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before injecting teduglutide,
What SPECIAL DIETARY instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do IF I FORGET to take a dose?
Inject the missed dose as soon as you remember it that day. Inject the next dose the next day at the same time you normally inject it every day. Do not inject two doses on the same day.
What SIDE EFFECTS can this medicine cause?
Teduglutide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Teduglutide injection may make abnormal cells in your body grow faster and therefore increase your risk of developing cancer. Talk to your doctor about the risks of taking this medication.
Teduglutide injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site] or by phone [1-800-332-1088].
What should I know about STORAGE and DISPOSAL of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze teduglutide. Use the teduglutide powder for injection by the expiration date on the "Use By" sticker on the kit. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain procedures and lab tests to check your body's response to teduglutide injection.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.