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Irritable Bowel Syndrome(Functional Colitis; IBS; Intestinal Neurosis; Irritable Colon; Laxative Colitis; Mucous Colitis; Nervous Indigestion; Spastic Colon)DefinitionIrritable bowel syndrome (IBS) is a chronic disorder of the intestines. IBS does not cause inflammation and does not lead to a more serious condition. CausesThe cause is unknown. With IBS, the muscles in the colon do not work normally and may spasm. If you have IBS, your colon may be more sensitive, reacting strongly to food and medication. Food allergies and certain bacteria may add to the symptoms. IBS may also occur after having the stomach flu (called gastroenteritis ). Risk FactorsThese factors increase your chance of developing IBS:
Tell your doctor if you have any of these risk factors. SymptomsSymptoms usually come and go and range from mild to severe. They include:
These factors may worsen your symptoms:
DiagnosisThe doctor will ask about your symptoms and medical history, and perform a physical exam. In many cases, a diagnosis can be made based on this. Since there is no diagnostic test for IBS, doctors have created criteria for making a diagnosis. Your doctor may order the following tests to rule out other conditions:
Your doctor may also screen you for celiac disease , which is more common in people with IBS.
Colonoscopy 2009 Nucleus Medical Media, Inc. TreatmentThere is no cure for IBS. Treatment focuses on controlling symptoms. DietThe following changes to your diet may help control symptoms:
Stress ManagementTalk to your doctor about ways to reduce stress , such as:
MedicationDepending on your symptoms, your doctor may prescribe:
RESOURCES: American College of Gastroenterology American Gastroenterological Association Irritable Bowel Syndrome Association CANADIAN RESOURCES Health Canada Irritable Bowel Syndrome Association References: Acidophilus and other probiotics. EBSCO Natural and Alternative Treatments website. Available at: http://www.ebscohost.com/thisTopic.php?marketID=15topicID=114 . Updated June 2008. Accessed July 15, 2008. Conn HF, Rakel RE. Conn's Current Therapy . Philadelphia, PA: WB Saunders Co; 2001. Drossman DA. Treatment for bacterial overgrowth in the irritable bowel syndrome. Ann Intern Med . 2006;145:626-628. Griffith HW. Griffith's 5-Minute Clinical Consult . Baltimore, MD: Lippincott Williams Wilkins; 1999. Halvorson HA, Schlett CD, Riddle MS. Postinfectious irritable bowel syndrome—a meta-analysis. Am J Gastroenterol . 2006;101:1894-1899. Irritable bowel syndrome. American Society of Colon and Rectal Surgeons website. Available at: http://www.fascrs.org/ . Update October 2007. Accessed July 15, 2008. Irritable bowel syndrome. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated December 2008. Accessed January 6, 2009. Irritable bowel syndrome (IBS). EBSCO Health Library website. Available at: http://www.ebscohost.com/thisTopic.php?marketID=15topicID=81 . Updated July 2008. Accessed July 7, 2008. Irritable bowel syndrome. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.niddk.nih.gov/ . Update September 2007. Accessed July 15, 2008. Murch S. Allergy and intestinal dysmotility—evidence of genuine causal linkage? Curr Opin Gastroenterol . 2006;22:664-668. Rubin G, De Wit N, Meineche-Schmidt V, Seifert B, Hall N, Hungin P. The diagnosis of IBS in primary care: consensus development using nominal group technique. Family Practitioner . 2006;23:687-692. Sleisenger MH, Fordtran JS, Feldman M, Scharschmidt B. Sleisenger Fordtran's Gastrointestinal and Liver Disease . 6th ed. Philadelphia, PA: WB Saunders Co; 1998. Talley NJ, Boyce PM, Jones M. Is the association between irritable bowel syndrome and abuse explained by neuroticism? A population based study. Gut. 1998;42: 47-53. Yan F, Polk DB. Probiotics as functional food in the treatment of diarrhea. Current Opinion in Clinical Nutrition and Metabolic Care . 2006;9:717-721. 9/26/2006 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Mueller-Lissner S, Tytgat GN, Paulo LG, et al. Placebo-and paracetamol-controlled study on the efficacy and tolerability of hyoscine butylbromide in the treatment of patients with recurrent crampy abdominal pain. Alimentary Pharmacology and Therapeutics . 2006;23:1741-1748. 4/10/2007 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : US Food and Drug Administration. FDA announces discontinued marketing of GI drug, Zelnorm, for safety reasons [press release]. March 30, 2007. US Food and Drug Administration website. Available at: http://www.fda.gov/bbs/topics/NEWS/2007/NEW01597.html . 1/6/2009 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Ford AC, Talley NJ, Spiegel BM, et al. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ . 2008;337:a2313. 10/9/2009 DynaMed Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Lee S, Wu J, Ma YL, Tsang A, Guo WJ, Sung J. Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study. Aliment Pharmacol Ther. 2009;30(6):643. 11/4/2009 DynaMed Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Ford AC, Brandt LJ, Young C, Chey WD, Foxx-Orenstein AE, Moayyedi P. Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2009;104(7):1831-1843. Last reviewed September 2009 by Daus Mahnke, MD Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2009 EBSCO Publishing All rights reserved.
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