High Cholesterol
(Cholesterol, High; Hypercholesterolemia)
En Español (Spanish Version)More InDepth Information on This Condition
Definition
Cholesterol is a type of lipid in the blood. High cholesterol is an abnormally high level of cholesterol in the blood.
There are different types of cholesterol in your blood including:
- Low density lipoproteins (LDL)—causes build up of cholesterol and other fats in the blood vessels. Known as bad cholesterol because high levels can cause disease in the arteries and heart disease.
- High density lipoproteins (HDL)—can remove cholesterol and other fats from the blood. Known as good cholesterol because it may protect against heart disease.
Symptoms
It is rare for high cholesterol to cause symptoms. However, high cholesterol can increase your risk of atherosclerosis . This is a dangerous hardening of the arteries. It can block the flow of blood. In some cases, a blocked or slowed blood flow may cause:
- Angina
- Heart attack
- Stroke
- Peripheral artery disease
- Other serious complications
Some people with high cholesterol may also have cholesterol deposits in tendons, under the eyes, or in the eye.
Atherosclerosis
Copyright © Nucleus Medical Media, Inc.
Diagnosis
The doctor will ask about your symptoms and medical history. Your doctor will ask about factors that may increase your risk of heart disease or stroke. A physical exam will be done.
A blood test will also be done. Blood will be sent to a lab to measure lipid levels in your blood including:
- Total cholesterol
- HDL cholesterol
- LDL cholesterol
- Triglycerides
Your doctor may do other tests to look for other conditions that can be associated with high cholesterol levels.
Treatment
Treatment is aimed at decreasing your cholesterol levels. Your doctor will also make recommendations to help you manage other risk factors for heart disease and stroke.
Nutritional Changes
Talk to your doctor about the best meal plan for you. Consider the following changes:
- Balance the amount of calories you are eating with the amount of calories you use through physical activity and basic body functions. This will help you reach or maintain a healthy weight.
- Eat a diet that is high in fruits and vegetables.
- Include foods that are whole grain and high in fiber.
- Eat fish at least twice per week.
- Limit foods with saturated fats, trans fats, or cholesterol.
- Avoid processed and refined sugars and starches. This includes white bread, white potatoes, white rice and simple sugars like soda.
- Choose and prepare foods with little or no salt
- If you drink alcohol, drink in moderation. This means two drinks per day for men and one drink per day for women.
Lifestyle Changes
- Begin a safe exercise program with the advice of your doctor.
- If you smoke, quit .
- If you are overweight, lose weight .
- Make sure other medical conditions such as high blood pressure and diabetes are being treated and controlled.
Cholesterol-Lowering Medication
Your doctor may prescribe medication. They will help lower your cholesterol.. Examples include:
- Statins
—have been shown to reduce mortality (death),
heart attacks
, and stroke.
Examples include:
- Lovastatin (Mevacor)
- Pravastatin (Pravachol)
- Atorvastatin (Lipitor)
- Simvastatin (Zocor)
- Rosuvastatin (Crestor)
- Gemfibrozil (Lopid)
- Fenofibrate (Tricor)
- Cholestyramine (Questran)
- Colestipol (Colestid)
- Niacin (Niacor)
- Ezetimibe (Zetia)
These medicines are best used as additions to diet and exercise. They should not be use in place of healthy lifestyle changes.
Prevention
To help reduce your chance of getting high cholesterol, follow the lifestyle and nutrition changes above.
RESOURCES:
American Heart Association
http://www.americanheart.org/
National Heart, Lung, and Blood Institute
http://www.nhlbi.nih.gov/
CANADIAN RESOURCES:
Canadian Cardiovascular Society
http://www.ccs.ca/
Heart and Stroke Foundation of Canada
http://ww2.heartandstroke.ca/
References:
Cholesterol. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/Cholesterol/Cholesterol_UCM_001089_SubHomePage.jsp. Accessed September 12, 2012.
Prevention and treatment of high cholesterol. American Heart Association website. Available at: http://www.heart.org/HEARTORG/Conditions/Cholesterol/PreventionTreatmentofHighCholesterol/Prevention-and-Treatment-of-High-Cholesterol_UCM_001215_Article.jsp . Published August 2012. Accessed September 12, 2012.
Lipid-lowering pharmacotherapy overview. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated July 3, 2012. Accessed September 12, 2012.
Third report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). National Cholesterol Education Program website. Available at: http://www.nhlbi.nih.gov/guidelines/cholesterol/index.htm . Updated 2004. Accessed September 12, 2012.
What is cholesterol? National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/hbc/ . Accessed September 12, 2012.
12/14/2009 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Ferdowsian HR, Barnard ND. Effects of plant-based diets on plasma lipids. Am J Cardiol . 2009;104(7):947-956.
Last reviewed September 2012 by Brian Randall, MD
Last updated Updated: 9/12/2012
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2010 EBSCO Publishing All rights reserved.
