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Chronic Obstructive Pulmonary Disease

Definition

Chronic obstructive pulmonary disease (COPD) makes it difficult to push air out of the lungs. The oxygen-poor air will build up. If the lungs are filled with this air, there is no room for fresh, oxygen-rich air. COPD includes:

The changes to lung tissue differ with the two diseases. However, the causes and treatment are similar.

Normal and Emphysemic Lung

Normal Lung and Emphysemic Lung

Copyright © Nucleus Medical Media, Inc.

Causes

COPD develops due to:

  • Cigarette smoking
  • Inhaling toxins or other irritants
  • Genetic predisposition can make a person's lungs more susceptible to damage from smoke or pollutants (includes alpha-1-antitrypsin deficiency)

Risk Factors

Factors that increase your chance of developing COPD include:

  • Smoking cigarettes
  • Long-term exposure to second-hand or passive smoke
  • Family members with COPD
  • Exposure to pollutants
  • History of frequent childhood lung infections
  • Age: 50 or older

Symptoms

Early symptoms of COPD include:

  • Coughing in the morning
  • Coughing up clear sputum (mucus from deep in the lungs)
  • Wheezing
  • Shortness of breath with activity

As the disease progresses, symptoms may include:

  • Increased shortness of breath
  • Choking sensation when lying flat
  • Fatigue
  • Trouble concentrating
  • Heart problems
  • Weight loss
  • Breathing through pursed lips
  • Desire to lean forward to improve breathing
  • More frequent flare-ups (periods of more severe symptoms)

Diagnosis

The doctor will ask about your symptoms and medical history. A physical exam will be done.

Tests may include:

  • Chest x-ray —x-rays of the chest that may detect signs of lung infection
  • CT scan —a type of x-ray that uses a computer to make pictures of structures inside the chest
  • Blood tests—to assess the amount of oxygen and carbon dioxide in the blood
  • Lung function tests

Treatment

There is no treatment to cure COPD. Treatment aims to ease symptoms and improve quality of life.

Treatment includes:

Smoking Cessation

Quitting smoking slows the disease. Doctors consider it the most important part of treatment. Smoking cessation programs may include behavior modification and medicines to help you quit.

Environmental Management

Limit the number of irritants in the air you breathe. It may help make breathing easier. Avoid smoke, dust, smog, extreme heat or cold, and high altitudes.

Medication

Some may be taken by mouth. Nebulizers and inhalers deliver drugs directly to the lungs. Drugs for COPD may work in the following ways:

  • Opening the airways
  • Relaxing the breathing passages
  • Decreasing inflammation
  • Helping thin secretions and bring up mucus from the lungs
  • Treating lung infections (antibiotics): If you have chronic bronchitis and mild-to-moderate COPD, you may not need antibiotics. If you do need them, a study found that shorter antibiotic treatment (five days or less) is as effective as longer treatment (more than five days).

Vaccines

Get vaccinated against pneumonia and the flu . The flu vaccine may reduce COPD flare-ups.

Oxygen

A few people can benefit from getting oxygen. It is given to improve the air you breathe in. It increases the amount of available oxygen. This can increase energy levels and heart and brain function.

Exercise

Special exercises can strengthen chest muscles and make breathing easier. Physical activity builds endurance and improves quality of life. Yoga is an example of an exercise routine that may offer benefits for people with COPD.

Follow your doctor's recommendations for activity levels and restrictions.

Breathing and Coughing Techniques

Special methods of breathing can help bring more air into and force trapped air out of the lungs. Coughing helps clear the lungs of mucus.

Nutrition

  • Maintain a normal weight. Excess weight causes the lungs and heart to work harder.
  • Eat a healthy diet that is low in saturated fat and rich in fruits, vegetables, and whole grain foods.
  • Eat several small meals during the day. It makes breathing easier.
  • Avoid gas-producing foods. Large meals and excess gas swell the stomach, which pushes up on the diaphragm.
  • Drink fluids to keep mucus thin.

Lifestyle Changes

  • Pace your activities.
  • Learn relaxation techniques and other methods to manage stress.
  • Seek emotional support from professionals, family, and friends. Anxiety can increase the rate of respiration, making breathing more strenuous.

Surgery

A small number of patients may benefit from surgery, such as lung transplant.

Prevention

Take these steps to reduce your chance of developing COPD:

  • If you smoke, quit.
  • Avoid exposure to second-hand smoke.
  • Avoid exposure to air pollution or irritants.
  • Wear protective gear if exposed to irritants or toxins at work.

RESOURCES:

American Lung Association
http://www.lungusa.org/

National Lung Health Education Program
http://www.nlhep.org/

CANADIAN RESOURCES:

The Canadian Lung Association
http://www.lung.ca/

Health Canada
http://www.hc-sc.gc.ca/

References:

COPD fact sheet. American Lung Association website. Available at: http://www.lungusa.org/site/c.dvLUK9O0E/b.4061173/apps/s/content.asp?ct=3052283 . Accessed July 15, 2008.

Eisner MD, Balmes J, Katz PP, et al. Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease. Environmental Health: A Global Access Science Source . 2005;4:7.

It has a name: COPD. National Heart, Lung, and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/public/lung/copd/ . Accessed July 15, 2008.

Spirometry. National Lung Health Education Program website. Available at: http://www.nlhep.org/ . Accessed July 15, 2008.

6/4/2008 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : El Moussaoui R, Roede BM, Speelman P, Bresser P, Prins JM, Bossuyt PM. Abstract Short-course antibiotic treatment in acute exacerbations of chronic bronchitis and COPD: a meta2-analysis of double-blind studies. Thorax . 2008;63:415-422.

11/6/2009 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Poole P, Chacko E, Wood-Baker R, Cates CJ. Influenza vaccine for patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev . 2009;(4):CD002733.

12/14/2009 DynaMed's Systematic Literature Surveillance DynaMed's Systematic Literature Surveillance : Donesky-Cuenco D, Nguyen HQ, Paul S, Carrieri-Kohlman V. Yoga therapy decreases dyspnea-related distress and improves functional performance in people with chronic obstructive pulmonary disease: a pilot study. J Altern Complement Med . 2009;15:225-234.



Last reviewed September 2011 by Tajender S. Vasu, MD


Last updated Updated: 9/22/2011

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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