Farhan Rizvi, PhD 

Research Scientist


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Aurora Research Institute
960 N. 12th Street, Suite 4120
Milwaukee, WI  53233

Research Scientist Farhan Rizvi, PhD

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Overview

Dr. Rizvi brings significant experience in molecular biology, epigenetics, and fibroblast biology and cardiometabolic disease to Aurora Research Institute’s Center for Integrative Research on Cardiovascular Aging (CIRCA) bed to bench research program. His current translational research focuses on better understanding of molecular mechanisms of aging associated cardiac fibrosis in atrial fibrillation and heart failure, repurposing drugs to treat cardiac fibrosis and discovery of noninvasive biomarkers for prognosis and potential therapy of atrial fibrillation and heart failure.  He has also been involved in microRNA control of signal transduction in cardiac fibrosis and the discovery of circulating miRNA as noninvasive biomarker that will help identify patients at risk of postoperative complications, such as atrial fibrillation, heart failure and heart failure with a preserved ejection fraction.

Education

Doctorate, Cholesterol Metabolism
University of Mumbai, India

Master of Science, Life Science
Aligarh Muslim University, India

Bachelor of Science, Biology and Chemistry
Lucknow University, India

Professional highlights

Led study, Advance age and circulating miR423 are independent predictors of postoperative atrial fibrillation, highlighted by American Physiological Society following Cardiovascular Aging: New Frontiers and Old Friends conference, 2017
 
Early career reviewer, National Institutes of Health, 2017
 
Best Poster Award recipient, Aurora Scientific Day, 2016
 
Grant recipient, Biomarkers to identify patients at high risk for heart failure after cardiac surgery, David V. Uihlein Foundation, 2016
 
Cardiac Research Award recipient, Aurora Health Care Foundation, 2016
 
Cardiovascular Surgery Research Award recipient, Aurora Health Care Foundation, 2013-2014
 
Holds four international patents for discovery of antidiabetic and antidyslipidemic compound, 2002, 2004, 2005

Publications

Rizvi F, DeFranco A, Siddiqui R, Negmadjanov U, Emelyanova L, Holmuhamedov A, Ross G, Shi Y, Holmuhamedov E, Kress D, Tajik AJ, Jahangir A. Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin. Am J Physiol Cell Physiol. 2016;311:C330-339. 
 
Ross GR, Bajwa T Jr, Edwards S, Emelyanova L, Rizvi F, Holmuhamedov EL, Werner P, Downey FX, Tajik AJ, Jahangir A. Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart. Biol Open. 2017;6:326-332. 

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