A glioblastoma multiforme (GBM) is the most aggressive type of brain tumor. It is a tumor that arises from glial cells inside the brain (known as glioma). A large network of blood vessels makes it possible for astrocytes, the star-shaped cells that make up your connective brain tissue, to reproduce very quickly – making this condition especially acute. Cells that reproduce quickly create pressure inside the brain which causes a number of the symptoms of a gliobastoma.



Glioblastoma symptoms may include: 

  • Headaches 
  • Nausea or vomiting
  • Loss of muscle function
  • Muscle weakness  
  • Vision changes
  • Memory and speech problems
  • Seizures


To diagnosis a glioblastoma, your doctor will first ask about your symptoms. He or she will likely recommend an MRI or a CT scan.

Find a Specialist

Our search tool can help you find the right neuroscience specialist.

Treatment Options

Dr. Amin Kassam, vice president for Neurosciences at Aurora Health Care, explains the Expanded Endonasal Approach, a minimally invasive surgery technique.

Glioblastoma treatment options may include:

  • The Expanded Endonasal Approach (EEA), a minimally invasive procedure in which the tumor is removed through the nasal passages, resulting in no incisions, a shorter hospital stay and faster recovery than conventional surgery.
  • BrainPath® technology, a minimally invasive procedure to access the tumor through a dime-sized channel, or port. 
  • Chemotherapy, which uses cancer-fighting drugs to stop the growth of tumors.
  • Stereotactic radiotherapy, which uses high-energy radiation to treat the tumor. This may include CyberKnife® radiosurgery, in which a non-invasive, robotic system delivers high doses of radiation to tumors with pinpoint accuracy. 
  • Traditional whole-brain radiation may also be used, particularly on tumors that have spread, or metastasized.

Medical Advancement for What Matters Most

When you’re diagnosed with a terminal brain tumor, every second counts. This is why our cancer experts have brought Optune® to Aurora – the first FDA-approved treatment in 12 years that’s been proven to extend life expectancy for those with glioblastoma.

Find a Specialist

Our search tool can help you find the right neuroscience specialist.

Get a Second  Opinion

Knowing all your options can make life's toughest decisions a little easier.

Your Life Your Health

myAurora makes it easy to manage your care online, anytime.